β-Glucuronidases of opportunistic bacteria are the major contributors to xenobiotic-induced toxicity in the gut
Abstract Gut bacterial β-D-glucuronidases (GUSs) catalyze the removal of glucuronic acid from liver-produced β-D-glucuronides. These reactions can have deleterious consequences when they reverse xenobiotic metabolism. The human gut contains hundreds of GUSs of variable sequences and structures. To u...
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Autores principales: | , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Acceso en línea: | https://doaj.org/article/0b6371ff0cd6400d83e8e0397189f8c8 |
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