Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival

Retrotransposons are usually dormant in healthy tissue, but become activated during malignancy. Here, in colorectal cancer, Cajuso et al. show that retrotransposon activity associates with clinical features of the disease.

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Autores principales:	Tatiana Cajuso, Päivi Sulo, Tomas Tanskanen, Riku Katainen, Aurora Taira, Ulrika A. Hänninen, Johanna Kondelin, Linda Forsström, Niko Välimäki, Mervi Aavikko, Eevi Kaasinen, Ari Ristimäki, Selja Koskensalo, Anna Lepistö, Laura Renkonen-Sinisalo, Toni Seppälä, Teijo Kuopio, Jan Böhm, Jukka-Pekka Mecklin, Outi Kilpivaara, Esa Pitkänen, Kimmo Palin, Lauri A. Aaltonen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0b6a406f2deb41ea96cf45072af0e221
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spelling	oai:doaj.org-article:0b6a406f2deb41ea96cf45072af0e2212021-12-02T17:01:33ZRetrotransposon insertions can initiate colorectal cancer and are associated with poor survival10.1038/s41467-019-11770-02041-1723https://doaj.org/article/0b6a406f2deb41ea96cf45072af0e2212019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11770-0https://doaj.org/toc/2041-1723Retrotransposons are usually dormant in healthy tissue, but become activated during malignancy. Here, in colorectal cancer, Cajuso et al. show that retrotransposon activity associates with clinical features of the disease.Tatiana CajusoPäivi SuloTomas TanskanenRiku KatainenAurora TairaUlrika A. HänninenJohanna KondelinLinda ForsströmNiko VälimäkiMervi AavikkoEevi KaasinenAri RistimäkiSelja KoskensaloAnna LepistöLaura Renkonen-SinisaloToni SeppäläTeijo KuopioJan BöhmJukka-Pekka MecklinOuti KilpivaaraEsa PitkänenKimmo PalinLauri A. AaltonenNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tatiana Cajuso Päivi Sulo Tomas Tanskanen Riku Katainen Aurora Taira Ulrika A. Hänninen Johanna Kondelin Linda Forsström Niko Välimäki Mervi Aavikko Eevi Kaasinen Ari Ristimäki Selja Koskensalo Anna Lepistö Laura Renkonen-Sinisalo Toni Seppälä Teijo Kuopio Jan Böhm Jukka-Pekka Mecklin Outi Kilpivaara Esa Pitkänen Kimmo Palin Lauri A. Aaltonen Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival
description	Retrotransposons are usually dormant in healthy tissue, but become activated during malignancy. Here, in colorectal cancer, Cajuso et al. show that retrotransposon activity associates with clinical features of the disease.
format	article
author	Tatiana Cajuso Päivi Sulo Tomas Tanskanen Riku Katainen Aurora Taira Ulrika A. Hänninen Johanna Kondelin Linda Forsström Niko Välimäki Mervi Aavikko Eevi Kaasinen Ari Ristimäki Selja Koskensalo Anna Lepistö Laura Renkonen-Sinisalo Toni Seppälä Teijo Kuopio Jan Böhm Jukka-Pekka Mecklin Outi Kilpivaara Esa Pitkänen Kimmo Palin Lauri A. Aaltonen
author_facet	Tatiana Cajuso Päivi Sulo Tomas Tanskanen Riku Katainen Aurora Taira Ulrika A. Hänninen Johanna Kondelin Linda Forsström Niko Välimäki Mervi Aavikko Eevi Kaasinen Ari Ristimäki Selja Koskensalo Anna Lepistö Laura Renkonen-Sinisalo Toni Seppälä Teijo Kuopio Jan Böhm Jukka-Pekka Mecklin Outi Kilpivaara Esa Pitkänen Kimmo Palin Lauri A. Aaltonen
author_sort	Tatiana Cajuso
title	Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival
title_short	Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival
title_full	Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival
title_fullStr	Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival
title_full_unstemmed	Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival
title_sort	retrotransposon insertions can initiate colorectal cancer and are associated with poor survival
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/0b6a406f2deb41ea96cf45072af0e221
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Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival

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