Puf6 primes 60S pre-ribosome nuclear export at low temperature

Puf6 primes 60S pre-ribosome nuclear export at low temperature

Ribosome biogenesis is crucially dependent on proper rRNA folding, a process assisted by chaperones. Here the authors reveal how Puf6 promotes correct rRNA folding at low temperature, a condition where mis-paired RNA folding intermediates frequently accumulate.

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Bibliographic Details
Main Authors: Stefan Gerhardy, Michaela Oborská-Oplová, Ludovic Gillet, Richard Börner, Rob van Nues, Alexander Leitner, Erich Michel, Janusz J. Petkowski, Sander Granneman, Roland K. O. Sigel, Ruedi Aebersold, Vikram Govind Panse
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Science
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Online Access:https://doaj.org/article/0bae3de09764483c9083cf74b1da5f94
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https://doaj.org/article/0bae3de09764483c9083cf74b1da5f94

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