Puf6 primes 60S pre-ribosome nuclear export at low temperature

Ribosome biogenesis is crucially dependent on proper rRNA folding, a process assisted by chaperones. Here the authors reveal how Puf6 promotes correct rRNA folding at low temperature, a condition where mis-paired RNA folding intermediates frequently accumulate.

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Autores principales:	Stefan Gerhardy, Michaela Oborská-Oplová, Ludovic Gillet, Richard Börner, Rob van Nues, Alexander Leitner, Erich Michel, Janusz J. Petkowski, Sander Granneman, Roland K. O. Sigel, Ruedi Aebersold, Vikram Govind Panse
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0bae3de09764483c9083cf74b1da5f94
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spelling	oai:doaj.org-article:0bae3de09764483c9083cf74b1da5f942021-12-02T17:06:27ZPuf6 primes 60S pre-ribosome nuclear export at low temperature10.1038/s41467-021-24964-22041-1723https://doaj.org/article/0bae3de09764483c9083cf74b1da5f942021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24964-2https://doaj.org/toc/2041-1723Ribosome biogenesis is crucially dependent on proper rRNA folding, a process assisted by chaperones. Here the authors reveal how Puf6 promotes correct rRNA folding at low temperature, a condition where mis-paired RNA folding intermediates frequently accumulate.Stefan GerhardyMichaela Oborská-OplováLudovic GilletRichard BörnerRob van NuesAlexander LeitnerErich MichelJanusz J. PetkowskiSander GrannemanRoland K. O. SigelRuedi AebersoldVikram Govind PanseNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Stefan Gerhardy Michaela Oborská-Oplová Ludovic Gillet Richard Börner Rob van Nues Alexander Leitner Erich Michel Janusz J. Petkowski Sander Granneman Roland K. O. Sigel Ruedi Aebersold Vikram Govind Panse Puf6 primes 60S pre-ribosome nuclear export at low temperature
description	Ribosome biogenesis is crucially dependent on proper rRNA folding, a process assisted by chaperones. Here the authors reveal how Puf6 promotes correct rRNA folding at low temperature, a condition where mis-paired RNA folding intermediates frequently accumulate.
format	article
author	Stefan Gerhardy Michaela Oborská-Oplová Ludovic Gillet Richard Börner Rob van Nues Alexander Leitner Erich Michel Janusz J. Petkowski Sander Granneman Roland K. O. Sigel Ruedi Aebersold Vikram Govind Panse
author_facet	Stefan Gerhardy Michaela Oborská-Oplová Ludovic Gillet Richard Börner Rob van Nues Alexander Leitner Erich Michel Janusz J. Petkowski Sander Granneman Roland K. O. Sigel Ruedi Aebersold Vikram Govind Panse
author_sort	Stefan Gerhardy
title	Puf6 primes 60S pre-ribosome nuclear export at low temperature
title_short	Puf6 primes 60S pre-ribosome nuclear export at low temperature
title_full	Puf6 primes 60S pre-ribosome nuclear export at low temperature
title_fullStr	Puf6 primes 60S pre-ribosome nuclear export at low temperature
title_full_unstemmed	Puf6 primes 60S pre-ribosome nuclear export at low temperature
title_sort	puf6 primes 60s pre-ribosome nuclear export at low temperature
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0bae3de09764483c9083cf74b1da5f94
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Puf6 primes 60S pre-ribosome nuclear export at low temperature

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