Focal Adhesion Kinase Regulates Hepatic Stellate Cell Activation and Liver Fibrosis

Focal Adhesion Kinase Regulates Hepatic Stellate Cell Activation and Liver Fibrosis

Abstract Understanding the underlying molecular mechanisms of liver fibrosis is important to develop effective therapy. Herein, we show that focal-adhesion-kinse (FAK) plays a key role in promoting hepatic stellate cells (HSCs) activation in vitro and liver fibrosis progression in vivo. FAK activati...

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Autores principales: Xue-Ke Zhao, Lei Yu, Ming-Liang Cheng, Pulin Che, Yin-Ying Lu, Quan Zhang, Mao Mu, Hong Li, Li-Li Zhu, Juan-Juan Zhu, Meng Hu, Po Li, Yue-Dong Liang, Xin-Hua Luo, Yi-Ju Cheng, Zhi-Xiang Xu, Qiang Ding
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
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Science
Q
Acceso en línea:https://doaj.org/article/0be84a8d4f6043a6b8939f2069666e82
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https://doaj.org/article/0be84a8d4f6043a6b8939f2069666e82

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