Structure of the mini-RNA-guided endonuclease CRISPR-Cas12j3

The Class 2 family of CRISPR nucleases named Cas12j, which shares only low sequence identity with other CRISPR nucleases was recently identified in the biggiephage clade of phages. Here, the authors present the cryo-EM structure of a functional Cas12j3−crRNA complex in the post-catalytic state and d...

Full description

Saved in:
Bibliographic Details
Main Authors: Arturo Carabias, Anders Fuglsang, Piero Temperini, Tillmann Pape, Nicholas Sofos, Stefano Stella, Simon Erlendsson, Guillermo Montoya
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Q
Online Access:https://doaj.org/article/0c04ac7b346d45d1bfa7aa86df769b74
Tags: Add Tag
No Tags, Be the first to tag this record!