Detection of MSH2 Gene Methylation in Extramammary Paget’s Disease by Methylation-Sensitive High-Resolution Melting Analysis

Background. Extramammary Paget’s disease (EMPD) is a rare skin tumor. Hypermethylation in the MSH2 promoter resulting in the downregulation of its protein expression shows a high detection rate in EMPD tumor tissue, which indicates that the methylation of MSH2 may play an important role in the patho...

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Autores principales: Liu Dong, Yingfeng Zhu, Liting Wu, Qiaoan Zhang, Feng Xu, Xinju Zhang, Xiao Xu, Yiting Tang, Guoqiang Ren, Zhihua Kang, Ming Guan
Formato: article
Lenguaje:EN
Publicado: Hindawi Limited 2021
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Acceso en línea:https://doaj.org/article/0c12d2a225ad40feaec04452c394e83b
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