Selective cytotoxicity of a novel immunotoxin based on pulchellin A chain for cells expressing HIV envelope

Abstract Immunotoxins (ITs), which consist of antibodies conjugated to toxins, have been proposed as a treatment for cancer and chronic infections. To develop and improve the ITs, different toxins such as ricin, have been used, aiming for higher efficacy against target cells. The toxin pulchellin, i...

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Autores principales: Mohammad Sadraeian, Francisco E. G. Guimarães, Ana P. U. Araújo, David K. Worthylake, Louis Jr. LeCour, Seth H. Pincus
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/0c255a1dc2eb4c78b4fafd46e461bdcf
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