Inverting family GH156 sialidases define an unusual catalytic motif for glycosidase action

Sialidases are glycoside hydrolases that cleave sialosides. Here the authors define the 3-D structure, alone and in complex with products and inhibitors, of the CAZy family GH156 sialidase, EnvSia156, showing it displays a catalytical (β/α) 8-barrel domain distinct from other sialidases and allowing...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Pedro Bule, Léa Chuzel, Elena Blagova, Liang Wu, Melissa A. Gray, Bernard Henrissat, Erdmann Rapp, Carolyn R. Bertozzi, Christopher H. Taron, Gideon J. Davies
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Q
Acceso en línea:https://doaj.org/article/0c2efbe0238a4ca8b32604be548a3735
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!