MiR-20a-5p functions as a potent tumor suppressor by targeting PPP6C in acute myeloid leukemia.

Acute myeloid leukemia (AML) is as a highly aggressive and heterogeneous hematological malignancy. MiR-20a-5p has been reported to function as an oncogene or tumor suppressor in several tumors, but the clinical significance and regulatory mechanisms of miR-20a-5p in AML cells have not been fully und...

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Autores principales: Fengchang Bao, Lei Zhang, Xiaohang Pei, Cheng Lian, Yanhui Liu, Hongna Tan, Pingchong Lei
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/0c417fb8567e4269b36a5b936c5ea5d7
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