Selection of microsatellite markers for bladder cancer diagnosis without the need for corresponding blood.

Microsatellite markers are used for loss-of-heterozygosity, allelic imbalance and clonality analyses in cancers. Usually, tumor DNA is compared to corresponding normal DNA. However, normal DNA is not always available and can display aberrant allele ratios due to copy number variations in the genome....

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Autores principales: Angela A G van Tilborg, Lucie C Kompier, Irene Lurkin, Ricardo Poort, Samira El Bouazzaoui, Kirstin van der Keur, Tahlita Zuiverloon, Lars Dyrskjot, Torben F Orntoft, Monique J Roobol, Ellen C Zwarthoff
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/0c4ca61dc0bf4194a0f747c3dda52fcb
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