RanBP2/Nup358 potentiates the translation of a subset of mRNAs encoding secretory proteins.

In higher eukaryotes, most mRNAs that encode secreted or membrane-bound proteins contain elements that promote an alternative mRNA nuclear export (ALREX) pathway. Here we report that ALREX-promoting elements also potentiate translation in the presence of upstream nuclear factors. These RNA elements...

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Autores principales: Kohila Mahadevan, Hui Zhang, Abdalla Akef, Xianying A Cui, Serge Gueroussov, Can Cenik, Frederick P Roth, Alexander F Palazzo
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/0c5c8dfdf40543e787124ba6c96ece5e
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