Reactive Oxygen Species (ROS) Are Not a Key Determinant for Zika Virus-Induced Apoptosis in SH-SY5Y Neuroblastoma Cells

Reactive Oxygen Species (ROS) Are Not a Key Determinant for Zika Virus-Induced Apoptosis in SH-SY5Y Neuroblastoma Cells

Introduction: ZIKV is a highly neurotropic virus that can cause the death of infected neuroprogenitor cells through mitochondrial damage and intrinsic apoptotic signaling. In this context, the role of reactive oxygen species (ROS) in neuronal cell death caused by ZIKV still remains elusive. Objectiv...

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Main Authors: Leila Rodrigues de Mendonça-Vieira, Conceição Elidianne Aníbal-Silva, Armando Menezes-Neto, Elisa de Almeida Neves Azevedo, Nágela Ghabdan Zanluqui, Jean Pierre Schatzmann Peron, Rafael Freitas de Oliveira Franca
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
Zika Virus
SH-SY5Y cell line
apoptosis
N-acetylcysteine
oxidative stress
Microbiology
QR1-502
Online Access:https://doaj.org/article/0c6d66e79b744bc58a392e2639c3f8dd
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https://doaj.org/article/0c6d66e79b744bc58a392e2639c3f8dd

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