Osmotic modulation of chromatin impacts on efficiency and kinetics of cell fate modulation

Abstract Chromatin structure is a major regulator of transcription and gene expression. Herein we explore the use of osmotic modulation to modify the chromatin structure and reprogram gene expression. In this study we use the extracellular osmotic pressure as a chromatin structure and transcriptiona...

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Autores principales: A. F. Lima, G. May, J. Díaz-Colunga, S. Pedreiro, A. Paiva, L. Ferreira, T. Enver, F. J. Iborra, R. Pires das Neves
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/0c79bbb7e5ff48728f838a4980fb54fc
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