Osmotic modulation of chromatin impacts on efficiency and kinetics of cell fate modulation

Abstract Chromatin structure is a major regulator of transcription and gene expression. Herein we explore the use of osmotic modulation to modify the chromatin structure and reprogram gene expression. In this study we use the extracellular osmotic pressure as a chromatin structure and transcriptiona...

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Bibliographic Details
Main Authors: A. F. Lima, G. May, J. Díaz-Colunga, S. Pedreiro, A. Paiva, L. Ferreira, T. Enver, F. J. Iborra, R. Pires das Neves
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
R
Q
Online Access:https://doaj.org/article/0c79bbb7e5ff48728f838a4980fb54fc
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