Transcriptional bursting is intrinsically caused by interplay between RNA polymerases on DNA

Transcriptional bursting is a potential source of cell-to-cell variability but the molecular mechanisms are unclear. Here the authors use single molecule imaging to analyse the kinetics of bursting on DNA and observe that bursting is an intrinsic property of RNA polymerases on DNA.

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Auteurs principaux: Keisuke Fujita, Mitsuhiro Iwaki, Toshio Yanagida
Format: article
Langue:EN
Publié: Nature Portfolio 2016
Sujets:
Q
Accès en ligne:https://doaj.org/article/0c9e7f8db8274ff6b23425e99cd09afb
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