Transcriptional bursting is intrinsically caused by interplay between RNA polymerases on DNA

Transcriptional bursting is a potential source of cell-to-cell variability but the molecular mechanisms are unclear. Here the authors use single molecule imaging to analyse the kinetics of bursting on DNA and observe that bursting is an intrinsic property of RNA polymerases on DNA.

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Autores principales: Keisuke Fujita, Mitsuhiro Iwaki, Toshio Yanagida
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/0c9e7f8db8274ff6b23425e99cd09afb
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