Transcriptional bursting is intrinsically caused by interplay between RNA polymerases on DNA

Transcriptional bursting is a potential source of cell-to-cell variability but the molecular mechanisms are unclear. Here the authors use single molecule imaging to analyse the kinetics of bursting on DNA and observe that bursting is an intrinsic property of RNA polymerases on DNA.

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Autores principales:	Keisuke Fujita, Mitsuhiro Iwaki, Toshio Yanagida
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0c9e7f8db8274ff6b23425e99cd09afb
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spelling	oai:doaj.org-article:0c9e7f8db8274ff6b23425e99cd09afb2021-12-02T14:39:12ZTranscriptional bursting is intrinsically caused by interplay between RNA polymerases on DNA10.1038/ncomms137882041-1723https://doaj.org/article/0c9e7f8db8274ff6b23425e99cd09afb2016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13788https://doaj.org/toc/2041-1723Transcriptional bursting is a potential source of cell-to-cell variability but the molecular mechanisms are unclear. Here the authors use single molecule imaging to analyse the kinetics of bursting on DNA and observe that bursting is an intrinsic property of RNA polymerases on DNA.Keisuke FujitaMitsuhiro IwakiToshio YanagidaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Keisuke Fujita Mitsuhiro Iwaki Toshio Yanagida Transcriptional bursting is intrinsically caused by interplay between RNA polymerases on DNA
description	Transcriptional bursting is a potential source of cell-to-cell variability but the molecular mechanisms are unclear. Here the authors use single molecule imaging to analyse the kinetics of bursting on DNA and observe that bursting is an intrinsic property of RNA polymerases on DNA.
format	article
author	Keisuke Fujita Mitsuhiro Iwaki Toshio Yanagida
author_facet	Keisuke Fujita Mitsuhiro Iwaki Toshio Yanagida
author_sort	Keisuke Fujita
title	Transcriptional bursting is intrinsically caused by interplay between RNA polymerases on DNA
title_short	Transcriptional bursting is intrinsically caused by interplay between RNA polymerases on DNA
title_full	Transcriptional bursting is intrinsically caused by interplay between RNA polymerases on DNA
title_fullStr	Transcriptional bursting is intrinsically caused by interplay between RNA polymerases on DNA
title_full_unstemmed	Transcriptional bursting is intrinsically caused by interplay between RNA polymerases on DNA
title_sort	transcriptional bursting is intrinsically caused by interplay between rna polymerases on dna
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/0c9e7f8db8274ff6b23425e99cd09afb
work_keys_str_mv	AT keisukefujita transcriptionalburstingisintrinsicallycausedbyinterplaybetweenrnapolymerasesondna AT mitsuhiroiwaki transcriptionalburstingisintrinsicallycausedbyinterplaybetweenrnapolymerasesondna AT toshioyanagida transcriptionalburstingisintrinsicallycausedbyinterplaybetweenrnapolymerasesondna
_version_	1718390696052785152

Transcriptional bursting is intrinsically caused by interplay between RNA polymerases on DNA

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