Common and distinct transcriptional signatures of mammalian embryonic lethality

The transcriptional signature of embryonic lethality has not been defined. Here, the authors, as part of the Deciphering the Mechanisms of Developmental Disorders programme, define genes causing murine embryonic lethality around E9.5 and identify developmental delay transcriptional signatures.

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Autores principales:	John E. Collins, Richard J. White, Nicole Staudt, Ian M. Sealy, Ian Packham, Neha Wali, Catherine Tudor, Cecilia Mazzeo, Angela Green, Emma Siragher, Edward Ryder, Jacqueline K. White, Irene Papatheodoru, Amy Tang, Anja Füllgrabe, Konstantinos Billis, Stefan H. Geyer, Wolfgang J. Weninger, Antonella Galli, Myriam Hemberger, Derek L. Stemple, Elizabeth Robertson, James C. Smith, Timothy Mohun, David J. Adams, Elisabeth M. Busch-Nentwich
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0cb4c8c4995e4b478eecfb999695d344
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spelling	oai:doaj.org-article:0cb4c8c4995e4b478eecfb999695d3442021-12-02T16:57:45ZCommon and distinct transcriptional signatures of mammalian embryonic lethality10.1038/s41467-019-10642-x2041-1723https://doaj.org/article/0cb4c8c4995e4b478eecfb999695d3442019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10642-xhttps://doaj.org/toc/2041-1723The transcriptional signature of embryonic lethality has not been defined. Here, the authors, as part of the Deciphering the Mechanisms of Developmental Disorders programme, define genes causing murine embryonic lethality around E9.5 and identify developmental delay transcriptional signatures.John E. CollinsRichard J. WhiteNicole StaudtIan M. SealyIan PackhamNeha WaliCatherine TudorCecilia MazzeoAngela GreenEmma SiragherEdward RyderJacqueline K. WhiteIrene PapatheodoruAmy TangAnja FüllgrabeKonstantinos BillisStefan H. GeyerWolfgang J. WeningerAntonella GalliMyriam HembergerDerek L. StempleElizabeth RobertsonJames C. SmithTimothy MohunDavid J. AdamsElisabeth M. Busch-NentwichNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q John E. Collins Richard J. White Nicole Staudt Ian M. Sealy Ian Packham Neha Wali Catherine Tudor Cecilia Mazzeo Angela Green Emma Siragher Edward Ryder Jacqueline K. White Irene Papatheodoru Amy Tang Anja Füllgrabe Konstantinos Billis Stefan H. Geyer Wolfgang J. Weninger Antonella Galli Myriam Hemberger Derek L. Stemple Elizabeth Robertson James C. Smith Timothy Mohun David J. Adams Elisabeth M. Busch-Nentwich Common and distinct transcriptional signatures of mammalian embryonic lethality
description	The transcriptional signature of embryonic lethality has not been defined. Here, the authors, as part of the Deciphering the Mechanisms of Developmental Disorders programme, define genes causing murine embryonic lethality around E9.5 and identify developmental delay transcriptional signatures.
format	article
author	John E. Collins Richard J. White Nicole Staudt Ian M. Sealy Ian Packham Neha Wali Catherine Tudor Cecilia Mazzeo Angela Green Emma Siragher Edward Ryder Jacqueline K. White Irene Papatheodoru Amy Tang Anja Füllgrabe Konstantinos Billis Stefan H. Geyer Wolfgang J. Weninger Antonella Galli Myriam Hemberger Derek L. Stemple Elizabeth Robertson James C. Smith Timothy Mohun David J. Adams Elisabeth M. Busch-Nentwich
author_facet	John E. Collins Richard J. White Nicole Staudt Ian M. Sealy Ian Packham Neha Wali Catherine Tudor Cecilia Mazzeo Angela Green Emma Siragher Edward Ryder Jacqueline K. White Irene Papatheodoru Amy Tang Anja Füllgrabe Konstantinos Billis Stefan H. Geyer Wolfgang J. Weninger Antonella Galli Myriam Hemberger Derek L. Stemple Elizabeth Robertson James C. Smith Timothy Mohun David J. Adams Elisabeth M. Busch-Nentwich
author_sort	John E. Collins
title	Common and distinct transcriptional signatures of mammalian embryonic lethality
title_short	Common and distinct transcriptional signatures of mammalian embryonic lethality
title_full	Common and distinct transcriptional signatures of mammalian embryonic lethality
title_fullStr	Common and distinct transcriptional signatures of mammalian embryonic lethality
title_full_unstemmed	Common and distinct transcriptional signatures of mammalian embryonic lethality
title_sort	common and distinct transcriptional signatures of mammalian embryonic lethality
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/0cb4c8c4995e4b478eecfb999695d344
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Common and distinct transcriptional signatures of mammalian embryonic lethality

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