Recovering protein-protein and domain-domain interactions from aggregation of IP-MS proteomics of coregulator complexes.
Coregulator proteins (CoRegs) are part of multi-protein complexes that transiently assemble with transcription factors and chromatin modifiers to regulate gene expression. In this study we analyzed data from 3,290 immuno-precipitations (IP) followed by mass spectrometry (MS) applied to human cell li...
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Main Authors: | , , , , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2011
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Online Access: | https://doaj.org/article/0cee1b71d698463991acce0891a5005a |
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