Defining the genomic signature of totipotency and pluripotency during early human development.

The genetic mechanisms governing human pre-implantation embryo development and the in vitro counterparts, human embryonic stem cells (hESCs), still remain incomplete. Previous global genome studies demonstrated that totipotent blastomeres from day-3 human embryos and pluripotent inner cell masses (I...

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Autores principales: Amparo Galan, Patricia Diaz-Gimeno, Maria Eugenia Poo, Diana Valbuena, Eva Sanchez, Veronica Ruiz, Joaquin Dopazo, David Montaner, Ana Conesa, Carlos Simon
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/0d0e73180e0e49bc948a228200fa8b93
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