Dectin-1 Is Required for Resistance to Coccidioidomycosis in Mice
ABSTRACT We assessed the role of Dectin-1 in the immune response to the pathogenic fungus Coccidioides, both in vitro and in vivo, using mice with a targeted mutation in Clec7a. Elicited peritoneal macrophages responded to formalin-killed spherules (FKS) and alkali-treated FKS by secreting proinflam...
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| Main Authors: | , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2013
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| Subjects: | |
| Online Access: | https://doaj.org/article/0d26f57a83574493a5ee87b848c2e7d4 |
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