Ionizing irradiation-induced Fgr in senescent cells mediates fibrosis

Abstract The role of cellular senescence in radiation-induced pulmonary fibrosis (RIPF) and the underlying mechanisms are unknown. We isolated radiation-induced senescent tdTOMp16 positive mesenchymal stem cells, established their absence of cell division, then measured levels of irradiation-induced...

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Autores principales: Amitava Mukherjee, Michael W. Epperly, Donna Shields, Wen Hou, Renee Fisher, Diala Hamade, Hong Wang, M. Saiful Huq, Riyue Bao, Tracy Tabib, Daisy Monier, Simon Watkins, Michael Calderon, Joel S. Greenberger
Formato: article
Lenguaje:EN
Publicado: Nature Publishing Group 2021
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Acceso en línea:https://doaj.org/article/0d506b65bfd24c52a6be862101f64fb6
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