Inhibition of ROS and upregulation of inflammatory cytokines by FoxO3a promotes survival against Salmonella typhimurium

FoxO3a signalling has limited influence over acute bacterial infection. Here the authors show that FoxO3a promotes survival of mice in response to chronic Salmonellatyphimurium infection by restraining oxidative stress and ERK signalling.

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Autores principales: Julie Joseph, Emmanuelle S. Ametepe, Naveen Haribabu, Gerard Agbayani, Lakshmi Krishnan, Alexandre Blais, Subash Sad
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/0d67533d355444dfb5e7aac87f2911a5
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