Inhibition of ROS and upregulation of inflammatory cytokines by FoxO3a promotes survival against Salmonella typhimurium

FoxO3a signalling has limited influence over acute bacterial infection. Here the authors show that FoxO3a promotes survival of mice in response to chronic Salmonellatyphimurium infection by restraining oxidative stress and ERK signalling.

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Autores principales:	Julie Joseph, Emmanuelle S. Ametepe, Naveen Haribabu, Gerard Agbayani, Lakshmi Krishnan, Alexandre Blais, Subash Sad
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0d67533d355444dfb5e7aac87f2911a5
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spelling	oai:doaj.org-article:0d67533d355444dfb5e7aac87f2911a52021-12-02T16:49:27ZInhibition of ROS and upregulation of inflammatory cytokines by FoxO3a promotes survival against Salmonella typhimurium10.1038/ncomms127482041-1723https://doaj.org/article/0d67533d355444dfb5e7aac87f2911a52016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12748https://doaj.org/toc/2041-1723FoxO3a signalling has limited influence over acute bacterial infection. Here the authors show that FoxO3a promotes survival of mice in response to chronic Salmonellatyphimurium infection by restraining oxidative stress and ERK signalling.Julie JosephEmmanuelle S. AmetepeNaveen HaribabuGerard AgbayaniLakshmi KrishnanAlexandre BlaisSubash SadNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Julie Joseph Emmanuelle S. Ametepe Naveen Haribabu Gerard Agbayani Lakshmi Krishnan Alexandre Blais Subash Sad Inhibition of ROS and upregulation of inflammatory cytokines by FoxO3a promotes survival against Salmonella typhimurium
description	FoxO3a signalling has limited influence over acute bacterial infection. Here the authors show that FoxO3a promotes survival of mice in response to chronic Salmonellatyphimurium infection by restraining oxidative stress and ERK signalling.
format	article
author	Julie Joseph Emmanuelle S. Ametepe Naveen Haribabu Gerard Agbayani Lakshmi Krishnan Alexandre Blais Subash Sad
author_facet	Julie Joseph Emmanuelle S. Ametepe Naveen Haribabu Gerard Agbayani Lakshmi Krishnan Alexandre Blais Subash Sad
author_sort	Julie Joseph
title	Inhibition of ROS and upregulation of inflammatory cytokines by FoxO3a promotes survival against Salmonella typhimurium
title_short	Inhibition of ROS and upregulation of inflammatory cytokines by FoxO3a promotes survival against Salmonella typhimurium
title_full	Inhibition of ROS and upregulation of inflammatory cytokines by FoxO3a promotes survival against Salmonella typhimurium
title_fullStr	Inhibition of ROS and upregulation of inflammatory cytokines by FoxO3a promotes survival against Salmonella typhimurium
title_full_unstemmed	Inhibition of ROS and upregulation of inflammatory cytokines by FoxO3a promotes survival against Salmonella typhimurium
title_sort	inhibition of ros and upregulation of inflammatory cytokines by foxo3a promotes survival against salmonella typhimurium
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/0d67533d355444dfb5e7aac87f2911a5
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Inhibition of ROS and upregulation of inflammatory cytokines by FoxO3a promotes survival against Salmonella typhimurium

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