Immunoprotective effect of an in silico designed multiepitope cancer vaccine with BORIS cancer-testis antigen target in a murine mammary carcinoma model

Abstract In our previous study, immunoinformatic tools were used to design a novel multiepitope cancer vaccine based on the most immunodominant regions of BORIS cancer-testis antigen. The final vaccine construct was an immunogenic, non-allergenic, and stable protein consisted of multiple cytotoxic T...

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Auteurs principaux: Elham Mahdevar, Amirhosein Kefayat, Ashkan Safavi, Amirhossein Behnia, Seyed Hossein Hejazi, Amaneh Javid, Fatemeh Ghahremani
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/0d75d01e8ac241a0b46dad98dbf92c3d
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