Estimation of Mycophenolic Acid Exposure in Heart Transplant Recipients by Population Pharmacokinetic and Limited Sampling Strategies

Purpose: The aim of this study is i) to establish a strategy to estimate the area under the curve of the dosing interval (AUC0–12h) of mycophenolic acid (MPA) in the heart transplant recipients and ii) to find the covariates that significantly affect the pharmacokinetics of MPA exposure.Methods: Thi...

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Autores principales: Xipei Wang, Yijin Wu, Jinsong Huang, Songgui Shan, Mingjie Mai, Jiade Zhu, Min Yang, Dewei Shang, Zheng Wu, Jinhua Lan, Shilong Zhong, Min Wu
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/0dc0b4ec8c2c4af6b69ac97df6a4e9d4
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