Re-evaluation of the action potential upstroke velocity as a measure of the Na+ current in cardiac myocytes at physiological conditions.

<h4>Background</h4>The SCN5A encoded sodium current (I(Na)) generates the action potential (AP) upstroke and is a major determinant of AP characteristics and AP propagation in cardiac myocytes. Unfortunately, in cardiac myocytes, investigation of kinetic properties of I(Na) with near-phy...

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Autores principales: Géza Berecki, Ronald Wilders, Berend de Jonge, Antoni C G van Ginneken, Arie O Verkerk
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/0dc9df0c1b414cd48ec6774fcc1d6f90
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