Re-evaluation of the action potential upstroke velocity as a measure of the Na+ current in cardiac myocytes at physiological conditions.
<h4>Background</h4>The SCN5A encoded sodium current (I(Na)) generates the action potential (AP) upstroke and is a major determinant of AP characteristics and AP propagation in cardiac myocytes. Unfortunately, in cardiac myocytes, investigation of kinetic properties of I(Na) with near-phy...
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Autores principales: | Géza Berecki, Ronald Wilders, Berend de Jonge, Antoni C G van Ginneken, Arie O Verkerk |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2010
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Materias: | |
Acceso en línea: | https://doaj.org/article/0dc9df0c1b414cd48ec6774fcc1d6f90 |
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