Unraveling the differential impact of PAHs and dioxin-like compounds on AKR1C3 reveals the EGFR extracellular domain as a critical determinant of the AHR response

Polycyclic aromatic hydrocarbons (PAHs), dioxin-like compounds (DLCs) and structurally-related environmental pollutants may contribute to the pathogenesis of various diseases and disorders, primarily by activating the aryl hydrocarbon receptor (AHR) and modulating downstream cellular responses. Acco...

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Autores principales: Christian Vogeley, Natalie C. Sondermann, Selina Woeste, Afaque A. Momin, Viola Gilardino, Frederick Hartung, Markus Heinen, Sophia K. Maaß, Melina Mescher, Marius Pollet, Katharina M. Rolfes, Christoph F.A. Vogel, Andrea Rossi, Dieter Lang, Stefan T. Arold, Motoki Nakamura, Thomas Haarmann-Stemmann
Formato: article
Lenguaje:EN
Publicado: Elsevier 2022
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Acceso en línea:https://doaj.org/article/0dcb6567f7fe460b927f10a91863a021
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