Evolution of DNA methylation in the human brain

DNA methylation plays an important role in brain development and function. Here, the authors compare whole-genome methylation in neurons and oligodendrocytes in humans, chimpanzees and macaques to reconstruct evolution of DNA methylation at cell-type level, including in regions associated with schiz...

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Auteurs principaux: Hyeonsoo Jeong, Isabel Mendizabal, Stefano Berto, Paramita Chatterjee, Thomas Layman, Noriyoshi Usui, Kazuya Toriumi, Connor Douglas, Devika Singh, Iksoo Huh, Todd M. Preuss, Genevieve Konopka, Soojin V. Yi
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/0dd08ea30d88455d976faaba5e8d47c1
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