Evolution of DNA methylation in the human brain

DNA methylation plays an important role in brain development and function. Here, the authors compare whole-genome methylation in neurons and oligodendrocytes in humans, chimpanzees and macaques to reconstruct evolution of DNA methylation at cell-type level, including in regions associated with schiz...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Hyeonsoo Jeong, Isabel Mendizabal, Stefano Berto, Paramita Chatterjee, Thomas Layman, Noriyoshi Usui, Kazuya Toriumi, Connor Douglas, Devika Singh, Iksoo Huh, Todd M. Preuss, Genevieve Konopka, Soojin V. Yi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0dd08ea30d88455d976faaba5e8d47c1
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:0dd08ea30d88455d976faaba5e8d47c1
record_format	dspace
spelling	oai:doaj.org-article:0dd08ea30d88455d976faaba5e8d47c12021-12-02T14:23:30ZEvolution of DNA methylation in the human brain10.1038/s41467-021-21917-72041-1723https://doaj.org/article/0dd08ea30d88455d976faaba5e8d47c12021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21917-7https://doaj.org/toc/2041-1723DNA methylation plays an important role in brain development and function. Here, the authors compare whole-genome methylation in neurons and oligodendrocytes in humans, chimpanzees and macaques to reconstruct evolution of DNA methylation at cell-type level, including in regions associated with schizophrenia heritability.Hyeonsoo JeongIsabel MendizabalStefano BertoParamita ChatterjeeThomas LaymanNoriyoshi UsuiKazuya ToriumiConnor DouglasDevika SinghIksoo HuhTodd M. PreussGenevieve KonopkaSoojin V. YiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hyeonsoo Jeong Isabel Mendizabal Stefano Berto Paramita Chatterjee Thomas Layman Noriyoshi Usui Kazuya Toriumi Connor Douglas Devika Singh Iksoo Huh Todd M. Preuss Genevieve Konopka Soojin V. Yi Evolution of DNA methylation in the human brain
description	DNA methylation plays an important role in brain development and function. Here, the authors compare whole-genome methylation in neurons and oligodendrocytes in humans, chimpanzees and macaques to reconstruct evolution of DNA methylation at cell-type level, including in regions associated with schizophrenia heritability.
format	article
author	Hyeonsoo Jeong Isabel Mendizabal Stefano Berto Paramita Chatterjee Thomas Layman Noriyoshi Usui Kazuya Toriumi Connor Douglas Devika Singh Iksoo Huh Todd M. Preuss Genevieve Konopka Soojin V. Yi
author_facet	Hyeonsoo Jeong Isabel Mendizabal Stefano Berto Paramita Chatterjee Thomas Layman Noriyoshi Usui Kazuya Toriumi Connor Douglas Devika Singh Iksoo Huh Todd M. Preuss Genevieve Konopka Soojin V. Yi
author_sort	Hyeonsoo Jeong
title	Evolution of DNA methylation in the human brain
title_short	Evolution of DNA methylation in the human brain
title_full	Evolution of DNA methylation in the human brain
title_fullStr	Evolution of DNA methylation in the human brain
title_full_unstemmed	Evolution of DNA methylation in the human brain
title_sort	evolution of dna methylation in the human brain
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0dd08ea30d88455d976faaba5e8d47c1
work_keys_str_mv	AT hyeonsoojeong evolutionofdnamethylationinthehumanbrain AT isabelmendizabal evolutionofdnamethylationinthehumanbrain AT stefanoberto evolutionofdnamethylationinthehumanbrain AT paramitachatterjee evolutionofdnamethylationinthehumanbrain AT thomaslayman evolutionofdnamethylationinthehumanbrain AT noriyoshiusui evolutionofdnamethylationinthehumanbrain AT kazuyatoriumi evolutionofdnamethylationinthehumanbrain AT connordouglas evolutionofdnamethylationinthehumanbrain AT devikasingh evolutionofdnamethylationinthehumanbrain AT iksoohuh evolutionofdnamethylationinthehumanbrain AT toddmpreuss evolutionofdnamethylationinthehumanbrain AT genevievekonopka evolutionofdnamethylationinthehumanbrain AT soojinvyi evolutionofdnamethylationinthehumanbrain
_version_	1718391409602461696

Evolution of DNA methylation in the human brain

Ejemplares similares