Genome of the fatal tapeworm Sparganum proliferum uncovers mechanisms for cryptic life cycle and aberrant larval proliferation

Kikuchi et al. sequence the genome of the fatal tapeworm Sparganum proliferum and a closely related non–life-threatening tapeworm Spirometra erinaceieuropaei, and describe its genomic features suggesting the natural history and molecular mechanisms underlying pathogenicity. Their findings indicate t...

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Autores principales:	Taisei Kikuchi, Mehmet Dayi, Vicky L. Hunt, Kenji Ishiwata, Atsushi Toyoda, Asuka Kounosu, Simo Sun, Yasunobu Maeda, Yoko Kondo, Belkisyole Alarcon de Noya, Oscar Noya, Somei Kojima, Toshiaki Kuramochi, Haruhiko Maruyama
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/0dd6f2e416d24802a0dc144cc251c86e
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spelling	oai:doaj.org-article:0dd6f2e416d24802a0dc144cc251c86e2021-12-02T15:02:48ZGenome of the fatal tapeworm Sparganum proliferum uncovers mechanisms for cryptic life cycle and aberrant larval proliferation10.1038/s42003-021-02160-82399-3642https://doaj.org/article/0dd6f2e416d24802a0dc144cc251c86e2021-05-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02160-8https://doaj.org/toc/2399-3642Kikuchi et al. sequence the genome of the fatal tapeworm Sparganum proliferum and a closely related non–life-threatening tapeworm Spirometra erinaceieuropaei, and describe its genomic features suggesting the natural history and molecular mechanisms underlying pathogenicity. Their findings indicate that nonordinal extracellular matrix coordination is important for its asexual reproduction, and suggest that loss of sexual maturity contributes to the fatal pathogenicity of S. proliferum to humans.Taisei KikuchiMehmet DayiVicky L. HuntKenji IshiwataAtsushi ToyodaAsuka KounosuSimo SunYasunobu MaedaYoko KondoBelkisyole Alarcon de NoyaOscar NoyaSomei KojimaToshiaki KuramochiHaruhiko MaruyamaNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Taisei Kikuchi Mehmet Dayi Vicky L. Hunt Kenji Ishiwata Atsushi Toyoda Asuka Kounosu Simo Sun Yasunobu Maeda Yoko Kondo Belkisyole Alarcon de Noya Oscar Noya Somei Kojima Toshiaki Kuramochi Haruhiko Maruyama Genome of the fatal tapeworm Sparganum proliferum uncovers mechanisms for cryptic life cycle and aberrant larval proliferation
description	Kikuchi et al. sequence the genome of the fatal tapeworm Sparganum proliferum and a closely related non–life-threatening tapeworm Spirometra erinaceieuropaei, and describe its genomic features suggesting the natural history and molecular mechanisms underlying pathogenicity. Their findings indicate that nonordinal extracellular matrix coordination is important for its asexual reproduction, and suggest that loss of sexual maturity contributes to the fatal pathogenicity of S. proliferum to humans.
format	article
author	Taisei Kikuchi Mehmet Dayi Vicky L. Hunt Kenji Ishiwata Atsushi Toyoda Asuka Kounosu Simo Sun Yasunobu Maeda Yoko Kondo Belkisyole Alarcon de Noya Oscar Noya Somei Kojima Toshiaki Kuramochi Haruhiko Maruyama
author_facet	Taisei Kikuchi Mehmet Dayi Vicky L. Hunt Kenji Ishiwata Atsushi Toyoda Asuka Kounosu Simo Sun Yasunobu Maeda Yoko Kondo Belkisyole Alarcon de Noya Oscar Noya Somei Kojima Toshiaki Kuramochi Haruhiko Maruyama
author_sort	Taisei Kikuchi
title	Genome of the fatal tapeworm Sparganum proliferum uncovers mechanisms for cryptic life cycle and aberrant larval proliferation
title_short	Genome of the fatal tapeworm Sparganum proliferum uncovers mechanisms for cryptic life cycle and aberrant larval proliferation
title_full	Genome of the fatal tapeworm Sparganum proliferum uncovers mechanisms for cryptic life cycle and aberrant larval proliferation
title_fullStr	Genome of the fatal tapeworm Sparganum proliferum uncovers mechanisms for cryptic life cycle and aberrant larval proliferation
title_full_unstemmed	Genome of the fatal tapeworm Sparganum proliferum uncovers mechanisms for cryptic life cycle and aberrant larval proliferation
title_sort	genome of the fatal tapeworm sparganum proliferum uncovers mechanisms for cryptic life cycle and aberrant larval proliferation
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0dd6f2e416d24802a0dc144cc251c86e
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Genome of the fatal tapeworm Sparganum proliferum uncovers mechanisms for cryptic life cycle and aberrant larval proliferation

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