Fibroadipogenic progenitors are responsible for muscle loss in limb girdle muscular dystrophy 2B
Fibroadipogenic precursor cells (FAPs) contribute to fibrosis and adipogenic replacement in muscular dystrophies. Here, the authors show that FAPs contribute to adipogenic loss in mouse models of limb girdle muscular dystrophy 2B via a mechanism dependent on expression of Annexin A2, and that this p...
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Auteurs principaux: | , , , , , , , |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
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Accès en ligne: | https://doaj.org/article/0de39a40d2af49bb9bb31819d111a9f9 |
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