Pathophysiology of Coagulopathy Induced by Traumatic Brain Injury Is Identical to That of Disseminated Intravascular Coagulation With Hyperfibrinolysis

Pathophysiology of Coagulopathy Induced by Traumatic Brain Injury Is Identical to That of Disseminated Intravascular Coagulation With Hyperfibrinolysis

Background: Traumatic brain injury (TBI)-associated coagulopathy is a widely recognized risk factor for secondary brain damage and contributes to poor clinical outcomes. Various theories, including disseminated intravascular coagulation (DIC), have been proposed regarding its pathomechanisms; no con...

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Auteurs principaux: Takeshi Wada, Atsushi Shiraishi, Satoshi Gando, Kazuma Yamakawa, Seitaro Fujishima, Daizoh Saitoh, Shigeki Kushimoto, Hiroshi Ogura, Toshikazu Abe, Toshihiko Mayumi, Junichi Sasaki, Joji Kotani, Naoshi Takeyama, Ryosuke Tsuruta, Kiyotsugu Takuma, Shin-ichiro Shiraishi, Yasukazu Shiino, Taka-aki Nakada, Kohji Okamoto, Yuichiro Sakamoto, Akiyoshi Hagiwara, Satoshi Fujimi, Yutaka Umemura, Yasuhiro Otomo
Format: article
Langue:EN
Publié: Frontiers Media S.A. 2021
Sujets:
disseminated intravascular coagulation
fibrinolysis
shock
thrombin
trauma-induced coagulopathy
traumatic brain injury
Medicine (General)
R5-920
Accès en ligne:https://doaj.org/article/0de51f1a742d4fddbfe0f001b841c3c7
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https://doaj.org/article/0de51f1a742d4fddbfe0f001b841c3c7

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