β-catenin-promoted cholesterol metabolism protects against cellular senescence in naked mole-rat cells

Woei-Yaw Chee et al. explore the molecular mechanisms of β-catenin involvement in cholesterol metabolism suppressing cellular senescence in naked mole-rat cells. The results of this study suggest that β-catenin in NMRs functions to offset senescence by regulating cholesterol metabolism, which may co...

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Autores principales: Woei-Yaw Chee, Yuriko Kurahashi, Junhyeong Kim, Kyoko Miura, Daisuke Okuzaki, Tohru Ishitani, Kentaro Kajiwara, Shigeyuki Nada, Hideyuki Okano, Masato Okada
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/0df8d8d8e4344801804091b33cbe145a
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