β-catenin-promoted cholesterol metabolism protects against cellular senescence in naked mole-rat cells

Woei-Yaw Chee et al. explore the molecular mechanisms of β-catenin involvement in cholesterol metabolism suppressing cellular senescence in naked mole-rat cells. The results of this study suggest that β-catenin in NMRs functions to offset senescence by regulating cholesterol metabolism, which may co...

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Autores principales:	Woei-Yaw Chee, Yuriko Kurahashi, Junhyeong Kim, Kyoko Miura, Daisuke Okuzaki, Tohru Ishitani, Kentaro Kajiwara, Shigeyuki Nada, Hideyuki Okano, Masato Okada
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/0df8d8d8e4344801804091b33cbe145a
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spelling	oai:doaj.org-article:0df8d8d8e4344801804091b33cbe145a2021-12-02T11:39:19Zβ-catenin-promoted cholesterol metabolism protects against cellular senescence in naked mole-rat cells10.1038/s42003-021-01879-82399-3642https://doaj.org/article/0df8d8d8e4344801804091b33cbe145a2021-03-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01879-8https://doaj.org/toc/2399-3642Woei-Yaw Chee et al. explore the molecular mechanisms of β-catenin involvement in cholesterol metabolism suppressing cellular senescence in naked mole-rat cells. The results of this study suggest that β-catenin in NMRs functions to offset senescence by regulating cholesterol metabolism, which may contribute to increased longevity in naked mole rats.Woei-Yaw CheeYuriko KurahashiJunhyeong KimKyoko MiuraDaisuke OkuzakiTohru IshitaniKentaro KajiwaraShigeyuki NadaHideyuki OkanoMasato OkadaNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Woei-Yaw Chee Yuriko Kurahashi Junhyeong Kim Kyoko Miura Daisuke Okuzaki Tohru Ishitani Kentaro Kajiwara Shigeyuki Nada Hideyuki Okano Masato Okada β-catenin-promoted cholesterol metabolism protects against cellular senescence in naked mole-rat cells
description	Woei-Yaw Chee et al. explore the molecular mechanisms of β-catenin involvement in cholesterol metabolism suppressing cellular senescence in naked mole-rat cells. The results of this study suggest that β-catenin in NMRs functions to offset senescence by regulating cholesterol metabolism, which may contribute to increased longevity in naked mole rats.
format	article
author	Woei-Yaw Chee Yuriko Kurahashi Junhyeong Kim Kyoko Miura Daisuke Okuzaki Tohru Ishitani Kentaro Kajiwara Shigeyuki Nada Hideyuki Okano Masato Okada
author_facet	Woei-Yaw Chee Yuriko Kurahashi Junhyeong Kim Kyoko Miura Daisuke Okuzaki Tohru Ishitani Kentaro Kajiwara Shigeyuki Nada Hideyuki Okano Masato Okada
author_sort	Woei-Yaw Chee
title	β-catenin-promoted cholesterol metabolism protects against cellular senescence in naked mole-rat cells
title_short	β-catenin-promoted cholesterol metabolism protects against cellular senescence in naked mole-rat cells
title_full	β-catenin-promoted cholesterol metabolism protects against cellular senescence in naked mole-rat cells
title_fullStr	β-catenin-promoted cholesterol metabolism protects against cellular senescence in naked mole-rat cells
title_full_unstemmed	β-catenin-promoted cholesterol metabolism protects against cellular senescence in naked mole-rat cells
title_sort	β-catenin-promoted cholesterol metabolism protects against cellular senescence in naked mole-rat cells
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0df8d8d8e4344801804091b33cbe145a
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β-catenin-promoted cholesterol metabolism protects against cellular senescence in naked mole-rat cells

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