Integrated metabolomics and transcriptomics reveal di(2-ethylhexyl) phthalate-induced mitochondrial dysfunction and glucose metabolism disorder through oxidative stress in rat liver

Di(2-ethylhexyl) phthalate (DEHP) is a ubiquitous pollutant that results in hepatotoxicity. However, an understanding of the systematic mechanism of hepatic injury caused by DEHP remains limited. Here, we performed a comprehensive metabolomics and transcriptomics analyses to describe hepatic respons...

Full description

Saved in:
Bibliographic Details
Main Authors: Gang Li, Chen-Yang Zhao, Qian Wu, Si-yuan Guan, Hong-Wei Jin, Xiao-Lin Na, Yun-Bo Zhang
Format: article
Language:EN
Published: Elsevier 2021
Subjects:
Online Access:https://doaj.org/article/0e05586acce84a35af33a8cc6fad52d3
Tags: Add Tag
No Tags, Be the first to tag this record!