Sensing Host Arginine Is Essential for <italic toggle="yes">Leishmania</italic> Parasites’ Intracellular Development
ABSTRACT Arginine homeostasis in lysosomes is critical for the growth and metabolism of mammalian cells. Phagolysosomes of macrophages are the niche where the parasitic protozoan Leishmania resides and causes human leishmaniasis. During infection, parasites encounter arginine deprivation, which is m...
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Autores principales: | Adele Goldman-Pinkovich, Sriram Kannan, Roni Nitzan-Koren, Madhu Puri, Harsh Pawar, Yael Bar-Avraham, Jacquelyn McDonald, Aakash Sur, Wen-Wei Zhang, Greg Matlashewski, Rentala Madhubala, Shulamit Michaeli, Peter J. Myler, Dan Zilberstein |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/0e194efdd6f54cbbaf5c38700237ad61 |
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