Sensing Host Arginine Is Essential for <italic toggle="yes">Leishmania</italic> Parasites’ Intracellular Development
ABSTRACT Arginine homeostasis in lysosomes is critical for the growth and metabolism of mammalian cells. Phagolysosomes of macrophages are the niche where the parasitic protozoan Leishmania resides and causes human leishmaniasis. During infection, parasites encounter arginine deprivation, which is m...
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Main Authors: | , , , , , , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2020
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Subjects: | |
Online Access: | https://doaj.org/article/0e194efdd6f54cbbaf5c38700237ad61 |
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