ALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries

Recent findings have challenged the established concept that retinoic acid (RA) induces foetal germ cells to enter meiosis. Here, Bowles et al. identify the enzyme ALDH1A1 as a source of ovarian RA that may induce meiosis even when other RA-synthetic enzymes are deleted.

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Autores principales: Josephine Bowles, Chun-Wei Feng, Kim Miles, Jessica Ineson, Cassy Spiller, Peter Koopman
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/0e22b65b446446819a8346023e0c02d8
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