ALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries

Recent findings have challenged the established concept that retinoic acid (RA) induces foetal germ cells to enter meiosis. Here, Bowles et al. identify the enzyme ALDH1A1 as a source of ovarian RA that may induce meiosis even when other RA-synthetic enzymes are deleted.

Guardado en:

Detalles Bibliográficos
Autores principales:	Josephine Bowles, Chun-Wei Feng, Kim Miles, Jessica Ineson, Cassy Spiller, Peter Koopman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0e22b65b446446819a8346023e0c02d8
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:0e22b65b446446819a8346023e0c02d8
record_format	dspace
spelling	oai:doaj.org-article:0e22b65b446446819a8346023e0c02d82021-12-02T16:50:55ZALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries10.1038/ncomms108452041-1723https://doaj.org/article/0e22b65b446446819a8346023e0c02d82016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10845https://doaj.org/toc/2041-1723Recent findings have challenged the established concept that retinoic acid (RA) induces foetal germ cells to enter meiosis. Here, Bowles et al. identify the enzyme ALDH1A1 as a source of ovarian RA that may induce meiosis even when other RA-synthetic enzymes are deleted.Josephine BowlesChun-Wei FengKim MilesJessica InesonCassy SpillerPeter KoopmanNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Josephine Bowles Chun-Wei Feng Kim Miles Jessica Ineson Cassy Spiller Peter Koopman ALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries
description	Recent findings have challenged the established concept that retinoic acid (RA) induces foetal germ cells to enter meiosis. Here, Bowles et al. identify the enzyme ALDH1A1 as a source of ovarian RA that may induce meiosis even when other RA-synthetic enzymes are deleted.
format	article
author	Josephine Bowles Chun-Wei Feng Kim Miles Jessica Ineson Cassy Spiller Peter Koopman
author_facet	Josephine Bowles Chun-Wei Feng Kim Miles Jessica Ineson Cassy Spiller Peter Koopman
author_sort	Josephine Bowles
title	ALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries
title_short	ALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries
title_full	ALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries
title_fullStr	ALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries
title_full_unstemmed	ALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries
title_sort	aldh1a1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/0e22b65b446446819a8346023e0c02d8
work_keys_str_mv	AT josephinebowles aldh1a1providesasourceofmeiosisinducingretinoicacidinmousefetalovaries AT chunweifeng aldh1a1providesasourceofmeiosisinducingretinoicacidinmousefetalovaries AT kimmiles aldh1a1providesasourceofmeiosisinducingretinoicacidinmousefetalovaries AT jessicaineson aldh1a1providesasourceofmeiosisinducingretinoicacidinmousefetalovaries AT cassyspiller aldh1a1providesasourceofmeiosisinducingretinoicacidinmousefetalovaries AT peterkoopman aldh1a1providesasourceofmeiosisinducingretinoicacidinmousefetalovaries
_version_	1718383019239145472

ALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries

Ejemplares similares