Crystal structure of Zen4 in the apo state reveals a missing conformation of kinesin

Kinesins are molecular motors that travel along microtubules through a nucleotide-dependent stepping mechanism. Here the authors present the crystal structure of Zen4 (kinesin-6) in an apo state that sheds light on a key stepping intermediate of kinesin.

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Detalles Bibliográficos
Autores principales: Ruifang Guan, Lei Zhang, Qian Peter Su, Keith J. Mickolajczyk, Geng-Yuan Chen, William O. Hancock, Yujie Sun, Yongfang Zhao, Zhucheng Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/0e277f1467ef49419410cb58269e9820
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