Gut Microbiota Metabolite Indole Propionic Acid Targets Tryptophan Biosynthesis in <italic toggle="yes">Mycobacterium tuberculosis</italic>
ABSTRACT Indole propionic acid (IPA), produced by the gut microbiota, is active against Mycobacterium tuberculosis in vitro and in vivo. However, its mechanism of action is unknown. IPA is the deamination product of tryptophan (Trp) and thus a close structural analog of this essential aromatic amino...
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| Main Authors: | , , , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2019
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| Subjects: | |
| Online Access: | https://doaj.org/article/0e2fba6e963346fe96944f4609ebe797 |
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