Critical Review of Gaps in the Diagnosis and Management of Drug-Induced Liver Injury Associated with Severe Cutaneous Adverse Reactions

Critical Review of Gaps in the Diagnosis and Management of Drug-Induced Liver Injury Associated with Severe Cutaneous Adverse Reactions

Drug-induced liver injury (DILI) encompasses the unexpected damage that drugs can cause to the liver. DILI may develop in the context of an immunoallergic syndrome with cutaneous manifestations, which are sometimes severe (SCARs). Nevirapine, allopurinol, anti-epileptics, sulfonamides, and antibioti...

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Main Authors: Marina Villanueva-Paz, Hao Niu, Antonio Segovia-Zafra, Inmaculada Medina-Caliz, Judith Sanabria-Cabrera, M. Isabel Lucena, Raúl J. Andrade, Ismael Alvarez-Alvarez
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
drug-induced liver injury
severe cutaneous adverse reactions
hypersensitivity
gaps
causality assessment
diagnosis
Medicine
R
Online Access:https://doaj.org/article/0e7d4805616d4ae79bc60801e6765a19
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https://doaj.org/article/0e7d4805616d4ae79bc60801e6765a19

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