CD4+ T cells from children with active juvenile idiopathic arthritis show altered chromatin features associated with transcriptional abnormalities

Abstract Juvenile idiopathic arthritis (JIA) is one of the most common chronic diseases in children. While clinical outcomes for patients with juvenile JIA have improved, the underlying biology of the disease and mechanisms underlying therapeutic response/non-response are poorly understood. We have...

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Autores principales: Evan Tarbell, Kaiyu Jiang, Teresa R. Hennon, Lucy Holmes, Sonja Williams, Yao Fu, Patrick M. Gaffney, Tao Liu, James N. Jarvis
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/0e8fdf375c2a4a7794e76c20764ae53c
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