A Dysfunctional Tricarboxylic Acid Cycle Enhances Fitness of <named-content content-type="genus-species">Staphylococcus epidermidis</named-content> During β-Lactam Stress

A Dysfunctional Tricarboxylic Acid Cycle Enhances Fitness of <named-content content-type="genus-species">Staphylococcus epidermidis</named-content> During β-Lactam Stress

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ABSTRACT A recent controversial hypothesis suggested that the bactericidal action of antibiotics is due to the generation of endogenous reactive oxygen species (ROS), a process requiring the citric acid cycle (tricarboxylic acid [TCA] cycle). To test this hypothesis, we assessed the ability of oxaci...

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Autores principales: Vinai Chittezham Thomas, Lauren C. Kinkead, Ashley Janssen, Carolyn R. Schaeffer, Keith M. Woods, Jill K. Lindgren, Jonathan M. Peaster, Sujata S. Chaudhari, Marat Sadykov, Joselyn Jones, Sameh M. Mohamadi AbdelGhani, Matthew C. Zimmerman, Kenneth W. Bayles, Greg A. Somerville, Paul D. Fey
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2013
Materias:
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/0e957108156f4ea585a2b4484c5cb040
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https://doaj.org/article/0e957108156f4ea585a2b4484c5cb040

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