A Broadly Implementable Research Course in Phage Discovery and Genomics for First-Year Undergraduate Students
ABSTRACT Engaging large numbers of undergraduates in authentic scientific discovery is desirable but difficult to achieve. We have developed a general model in which faculty and teaching assistants from diverse academic institutions are trained to teach a research course for first-year undergraduate...
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American Society for Microbiology
2014
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oai:doaj.org-article:0ea3a4eb4eae476f8b2d36ac7eff393c2021-11-15T15:45:10ZA Broadly Implementable Research Course in Phage Discovery and Genomics for First-Year Undergraduate Students10.1128/mBio.01051-132150-7511https://doaj.org/article/0ea3a4eb4eae476f8b2d36ac7eff393c2014-02-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.01051-13https://doaj.org/toc/2150-7511ABSTRACT Engaging large numbers of undergraduates in authentic scientific discovery is desirable but difficult to achieve. We have developed a general model in which faculty and teaching assistants from diverse academic institutions are trained to teach a research course for first-year undergraduate students focused on bacteriophage discovery and genomics. The course is situated within a broader scientific context aimed at understanding viral diversity, such that faculty and students are collaborators with established researchers in the field. The Howard Hughes Medical Institute (HHMI) Science Education Alliance Phage Hunters Advancing Genomics and Evolutionary Science (SEA-PHAGES) course has been widely implemented and has been taken by over 4,800 students at 73 institutions. We show here that this alliance-sourced model not only substantially advances the field of phage genomics but also stimulates students’ interest in science, positively influences academic achievement, and enhances persistence in science, technology, engineering, and mathematics (STEM) disciplines. Broad application of this model by integrating other research areas with large numbers of early-career undergraduate students has the potential to be transformative in science education and research training. IMPORTANCE Engagement of undergraduate students in scientific research at early stages in their careers presents an opportunity to excite students about science, technology, engineering, and mathematics (STEM) disciplines and promote continued interests in these areas. Many excellent course-based undergraduate research experiences have been developed, but scaling these to a broader impact with larger numbers of students is challenging. The Howard Hughes Medical Institute (HHMI) Science Education Alliance Phage Hunting Advancing Genomics and Evolutionary Science (SEA-PHAGES) program takes advantage of the huge size and diversity of the bacteriophage population to engage students in discovery of new viruses, genome annotation, and comparative genomics, with strong impacts on bacteriophage research, increased persistence in STEM fields, and student self-identification with learning gains, motivation, attitude, and career aspirations.Tuajuanda C. JordanSandra H. BurnettSusan CarsonSteven M. CarusoKari ClaseRandall J. DeJongJohn J. DennehyDee R. DenverDavid DunbarSarah C. R. ElginAnn M. FindleyChris R. GissendannerUrszula P. GolebiewskaNancy GuildGrant A. HartzogWendy H. GrilloGail P. HollowellLee E. HughesAllison JohnsonRodney A. KingLynn O. LewisWei LiFrank RosenzweigMichael R. RubinMargaret S. SahaJames SandozChristopher D. ShafferBarbara TaylorLouise TempleEdwin VazquezVassie C. WareLucia P. BarkerKevin W. BradleyDeborah Jacobs-SeraWelkin H. PopeDaniel A. RussellSteven G. CresawnDavid LopattoCheryl P. BaileyGraham F. HatfullAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 5, Iss 1 (2014) |
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DOAJ |
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EN |
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Microbiology QR1-502 |
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Microbiology QR1-502 Tuajuanda C. Jordan Sandra H. Burnett Susan Carson Steven M. Caruso Kari Clase Randall J. DeJong John J. Dennehy Dee R. Denver David Dunbar Sarah C. R. Elgin Ann M. Findley Chris R. Gissendanner Urszula P. Golebiewska Nancy Guild Grant A. Hartzog Wendy H. Grillo Gail P. Hollowell Lee E. Hughes Allison Johnson Rodney A. King Lynn O. Lewis Wei Li Frank Rosenzweig Michael R. Rubin Margaret S. Saha James Sandoz Christopher D. Shaffer Barbara Taylor Louise Temple Edwin Vazquez Vassie C. Ware Lucia P. Barker Kevin W. Bradley Deborah Jacobs-Sera Welkin H. Pope Daniel A. Russell Steven G. Cresawn David Lopatto Cheryl P. Bailey Graham F. Hatfull A Broadly Implementable Research Course in Phage Discovery and Genomics for First-Year Undergraduate Students |
| description |
ABSTRACT Engaging large numbers of undergraduates in authentic scientific discovery is desirable but difficult to achieve. We have developed a general model in which faculty and teaching assistants from diverse academic institutions are trained to teach a research course for first-year undergraduate students focused on bacteriophage discovery and genomics. The course is situated within a broader scientific context aimed at understanding viral diversity, such that faculty and students are collaborators with established researchers in the field. The Howard Hughes Medical Institute (HHMI) Science Education Alliance Phage Hunters Advancing Genomics and Evolutionary Science (SEA-PHAGES) course has been widely implemented and has been taken by over 4,800 students at 73 institutions. We show here that this alliance-sourced model not only substantially advances the field of phage genomics but also stimulates students’ interest in science, positively influences academic achievement, and enhances persistence in science, technology, engineering, and mathematics (STEM) disciplines. Broad application of this model by integrating other research areas with large numbers of early-career undergraduate students has the potential to be transformative in science education and research training. IMPORTANCE Engagement of undergraduate students in scientific research at early stages in their careers presents an opportunity to excite students about science, technology, engineering, and mathematics (STEM) disciplines and promote continued interests in these areas. Many excellent course-based undergraduate research experiences have been developed, but scaling these to a broader impact with larger numbers of students is challenging. The Howard Hughes Medical Institute (HHMI) Science Education Alliance Phage Hunting Advancing Genomics and Evolutionary Science (SEA-PHAGES) program takes advantage of the huge size and diversity of the bacteriophage population to engage students in discovery of new viruses, genome annotation, and comparative genomics, with strong impacts on bacteriophage research, increased persistence in STEM fields, and student self-identification with learning gains, motivation, attitude, and career aspirations. |
| format |
article |
| author |
Tuajuanda C. Jordan Sandra H. Burnett Susan Carson Steven M. Caruso Kari Clase Randall J. DeJong John J. Dennehy Dee R. Denver David Dunbar Sarah C. R. Elgin Ann M. Findley Chris R. Gissendanner Urszula P. Golebiewska Nancy Guild Grant A. Hartzog Wendy H. Grillo Gail P. Hollowell Lee E. Hughes Allison Johnson Rodney A. King Lynn O. Lewis Wei Li Frank Rosenzweig Michael R. Rubin Margaret S. Saha James Sandoz Christopher D. Shaffer Barbara Taylor Louise Temple Edwin Vazquez Vassie C. Ware Lucia P. Barker Kevin W. Bradley Deborah Jacobs-Sera Welkin H. Pope Daniel A. Russell Steven G. Cresawn David Lopatto Cheryl P. Bailey Graham F. Hatfull |
| author_facet |
Tuajuanda C. Jordan Sandra H. Burnett Susan Carson Steven M. Caruso Kari Clase Randall J. DeJong John J. Dennehy Dee R. Denver David Dunbar Sarah C. R. Elgin Ann M. Findley Chris R. Gissendanner Urszula P. Golebiewska Nancy Guild Grant A. Hartzog Wendy H. Grillo Gail P. Hollowell Lee E. Hughes Allison Johnson Rodney A. King Lynn O. Lewis Wei Li Frank Rosenzweig Michael R. Rubin Margaret S. Saha James Sandoz Christopher D. Shaffer Barbara Taylor Louise Temple Edwin Vazquez Vassie C. Ware Lucia P. Barker Kevin W. Bradley Deborah Jacobs-Sera Welkin H. Pope Daniel A. Russell Steven G. Cresawn David Lopatto Cheryl P. Bailey Graham F. Hatfull |
| author_sort |
Tuajuanda C. Jordan |
| title |
A Broadly Implementable Research Course in Phage Discovery and Genomics for First-Year Undergraduate Students |
| title_short |
A Broadly Implementable Research Course in Phage Discovery and Genomics for First-Year Undergraduate Students |
| title_full |
A Broadly Implementable Research Course in Phage Discovery and Genomics for First-Year Undergraduate Students |
| title_fullStr |
A Broadly Implementable Research Course in Phage Discovery and Genomics for First-Year Undergraduate Students |
| title_full_unstemmed |
A Broadly Implementable Research Course in Phage Discovery and Genomics for First-Year Undergraduate Students |
| title_sort |
broadly implementable research course in phage discovery and genomics for first-year undergraduate students |
| publisher |
American Society for Microbiology |
| publishDate |
2014 |
| url |
https://doaj.org/article/0ea3a4eb4eae476f8b2d36ac7eff393c |
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