BRK targets Dok1 for ubiquitin-mediated proteasomal degradation to promote cell proliferation and migration.
Breast tumor kinase (BRK), also known as protein tyrosine kinase 6 (PTK6), is a non-receptor tyrosine kinase overexpressed in more that 60% of human breast carcinomas. The overexpression of BRK has been shown to sensitize mammary epithelial cells to mitogenic signaling and to promote cell proliferat...
Enregistré dans:
| Auteurs principaux: | , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Public Library of Science (PLoS)
2014
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/0eb0e42ee72c498a98472e66fd3b4c9a |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|