Histamine-induced biphasic activation of RhoA allows for persistent RhoA signaling.
The small GTPase RhoA is a central signaling enzyme that is involved in various cellular processes such as cytoskeletal dynamics, transcription, and cell cycle progression. Many signal transduction pathways activate RhoA-for instance, Gαq-coupled Histamine 1 Receptor signaling via Gαq-dependent acti...
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Autores principales: | , , , , , |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2020
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Acceso en línea: | https://doaj.org/article/0ebb54bacf2e4652ac3dc47d3752c53f |
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