Priming mobilization of hair follicle stem cells triggers permanent loss of regeneration after alkylating chemotherapy

Hair follicles (HFs) are sensitive to chemotherapy but recover from quiescent HF stem cells, although sometimes chemotherapy results in permanent loss. Here, Kim et al. establish a model of permanent chemotherapy-induced alopecia to uncover the underlying mechanisms depleting human HF stem cells.

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Bibliographic Details
Main Authors: Jin Yong Kim, Jungyoon Ohn, Ji-Seon Yoon, Bo Mi Kang, Minji Park, Sookyung Kim, Woochan Lee, Sungjoo Hwang, Jong-Il Kim, Kyu Han Kim, Ohsang Kwon
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/0ebcac53511c43cd9ca4c49f28dcf1a2
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